Alexander Birke

Forschungsgebiete

  • Polypeptidische Polymerarchitekturen zum Transport für bioaktive Substanzen

Publikationen

  • Conejos-Sánchez, I.; Duro-Castano, A.; Birke, A.; Barz, M.; Vicent, M. J.
    A Controlled and Versatile NCA Polymerization Method for the Synthesis of Polypeptides.
    Polym. Chem. 2013, 4, 3182.

  • Birke, A.; Huesmann, D.; Kelsch, A.; Weilbächer, M.; Xie, J.; Bros, M.; Bopp, T.; Becker, C.; Landfester, K.; Barz, M.
    Polypeptoid-Block-Polypeptide Copolymers: Synthesis, Characterization, and Application of Amphiphilic Block Copolypept(o)ides in Drug Formulations and Miniemulsion Techniques.
    Biomacromolecules 2014, 15, 548–557.

  • Huesmann, D.; Birke, A.; Klinker, K.; Türk, S.; Räder, H. J.; Barz, M.
    Revisiting Secondary Structures in NCA Polymerization: Influences on the Analysis of Protected Polylysines.
    Macromolecules 2014, 47, 928–936.

  • deRonde, B. M.; Birke, A.; Tew, G. N.
    Design of Aromatic-Containing Cell-Penetrating Peptide Mimics with Structurally Modified π Electronics.
    Chem. Eur. J. 2014 doi: 10.1002/chem.201405381

  • Heller, P.; Birke, A.; Huesmann, D.; Weber, B.; Fischer, K.; Reske-Kunz, A.; Bros, M.; Barz, M.
    Introducing PeptoPlexes: Polylysine-block-Polysarcosine Based Polyplexes for Transfection of HEK 293T Cells.
    Macromol. Biosci. 2014 14: 1380–1395. doi: 10.1002/mabi.201400167

  • Heller, P.; Weber, B.; Birke, A.; Barz, M.
    Synthesis and Sequential Deprotection of Triblock Copolypept(o)ides Using Orthogonal Protective Group Chemistry​
    Macromol. Rapid Commun. 1/2015. doi: 10.1002/marc.201570001​

  • Heller, P.; Mohr, N.; Birke, A.; Weber, B.; Reske-Kunz, A.; Bros, M.; Barz, M.
    Directed Interactions of Block Copolypept(o)ides with Mannose-binding Receptors: PeptoMicelles Targeted to Cells of the Innate Immune System.
    Macromol. Biosci. 2015, 15: 63–73. doi: 10.1002/mabi.201400417

Adresse

Johannes Gutenberg-Universität Mainz
Institut für Organische Chemie
Duesbergweg 10-14
55099 Mainz

Tel: (+49-6131) 39-25467
Fax: (+49-6131) 39-24778